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Public release date: 27 April 2010
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Men with erectile dysfunction, low testosterone at higher risk of death from cardiovascular disease

New research at University of Florence, Italy, shows for the first time that men with erectile dysfunction and low testosterone have a higher than normal risk of dying from cardiovascular disease. In a previous work, the same research group shows that obesity is also associated with an impairment of blood flow to the penis, which in turn is also associated with cardiovascular disease in men with erectile dysfunction.

Italian researchers concluded that if you have erectile dysfunction, and if you have a very low testosterone level, then you are up to 7 times more likely to die from a major cardiac event than if you have erectile dysfunction and normal testosterone levels. It may be worth screening for testosterone deficiency in men with erectile dysfunction may help clinicians identify those at higher risk from cardiovascular events.

However, this is the first time that low testosterone is associated with higher death rates from heart disease in men with erectile dysfunction and at the moment researchers can't say whether low testosterone levels are the cause or the consequence of this higher risk.

At the same time, large-scale studies are needed to look at whether testosterone replacement therapy in at-risk men can prevent unnecessary deaths from heart disease

In obese men with erectile dysfunction, more than in leaner men with erectile dysfunction, impaired blood flow to the penis is associated with an increased risk of cardiovascular disease. Taking these results together, researchers can conclude that, referral for erectile dysfunction should become an opportunity - for the patient and for the doctor - to screen for general health. In one sense, the diagnosis of erectile dysfunction offers these patients a unique chance to undergo a medical examination and therefore to improve not only their sexual but, most importantly, their overall health.

Research was presented at the European Congress of Endocrinology

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SOURCE: European Society of Endocrinology



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