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Public release date: 05 May 2010
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Obese men more likely to have low testosterone than non-obese men
Obesity, a condition linked to heart disease and diabetes, now appears to be associated with another health problem,
but one that affects men only -- low testosterone levels.
A recent study conducted by University at Buffalo endocrinologists, showed that 40 percent of obese participants involved
in the Hypogonadism in Males (HIM) study had lower-than-normal testosterone readings.
Researchers hypothesized that obese men are more likely to have low testosterone than non-obese men, and that we would
find more low testosterone levels in
men with diabetes than in men without diabetes, both obese and non-obese. Study results confirmed these hypotheses,
showing a 40 percent higher prevalence of low testosterone in obese men compared to the non-obese participants.
Men with diabetes, whether obese or not, showed
reduction of testosterone levels than non-diabetic men across all weight categories. Testosterone levels decreased
significantly in both diabetic and non-diabetic men as BMI increased.
The Endocrine Society now recommends that all men with type 2 diabetes should have their testosterone levels measured.
This study shows that
men with excess body fat also have a very high prevalence of low testosterone levels, so physicians should consider screening obese non-diabetic men, as well, for low testosterone.
Taking into consideration that the fact that almost one-third of the U.S. is obese, these observations have profound
pathophysiological, clinical, epidemiological and public health implications.
According to study leader, in view of the high rates of subnormal testosterone in patients with obesity or diabetes,
testosterone concentrations should be measured
regularly in these populations, especially when these conditions occur together.
Results of a study are published online ahead of print in the journal Diabetes Care.
Source: Buffalo University
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