The association between low levels of testosterone and decline in physical performance is of great importance because testosterone supplementation could be used in ageing men to prevent strength loss and physical impairment. It is still unclear whether levels of total testosterone (TT) or free testosterone (FT) are prospective determinants of decline in physical performance and/or muscle strength and could potentially be used as early markers for the prevention or treatment of physical impairment.
Recently a research team used prospective data from two independent cohort studies in order to investigate whether low serum TT and FT concentrations in older men are associated with 3-year decline in physical performance and muscle strength.
The study findings suggest that lower testosterone levels are not associated with physical decline. Although this study suggests that decline in physical performance and strength is similar in men with high and low levels of testosterone, the magnitude of decline will be greater in men with low baseline physical performance scores and low baseline muscle strength. Finally experts agree that further studies are needed to confirm their results.
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