More recently, many elderly American Men used supplements of testosterone (the most important male hormone) to improve their bone styrength, muscle mass, libido and quality of life. Their number is still increasing despite the fact that the cardiovascular effects of chronic testosterone treatment in elderly men are largely unclear, and the safety of testosterone replacement has not been concluded.
Recently a research team has been using an animal model to investigate potential connevtion between testosterone supplements and cardiovascular and renal disease. The results suggest that testosterone supplementation of aging male promotes renal injury and thereby exacerbates hypertension. more info

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