A daily dose of an investigational drug, known as MK-677, which stimulates growth hormone secretion in the body can boost muscle mass in older adults, report researchers at the University of Virginia Health System.
Published in the November 4, 2008 issue of Annals of Internal Medicine, the study showed that levels of growth hormone (GH) and of insulin-like growth factor I (IGF- I) in seniors who took MK-677 increased to those found in healthy young adults.
The drug restored 20 percent of muscle mass loss associated with normal aging.
The search for anti-frailty medications has become increasingly important because the average American is expected to live into his or her 80s, and most seniors want to stay strong enough to remain independent as they age.
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