A new study says sex hormone levels affect the risk of broken bones in older men.The finding comes from a study that included 1,436 men age 65 and older who had their sex hormone levels measured periodically for about five years. The researchers concluded that men with low levels of estradiol or high levels of sex hormone binding globulin (SHBG) were more likely to suffer osteoporotic fractures.
In addition, men with low levels of testosterone and estradiol combined with high levels of SHBG were more than three times as likely to break a bone as men with average levels of the hormones, the study found.
Testosterone is the main male sex hormone. Estradiol provides most estrogen effects in men and women. SHBG is a protein that binds to testosterone and estradiol in the blood. It’s known to reduce circulating sex steroid concentrations and has previously been linked with fracture risk.
The study will appear in the September issue of the Journal of Clinical Endocrinology & Metabolism.
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