According to a new study at University of California, San Diego, older men with high levels of the hormone IGF-I (insulin-like growth factor 1) are at increased risk of cancer death, independent of age, lifestyle and cancer history.
IGF-I is a protein hormone. It’s structure is similar to insulin and is regulated in the body by growth hormone. Levels of growth hormone and IGF-I decline progressively with age in both men and women and this drop is thought to be related to deteriorating health conditions found with advanced age. In an attempt to combat aging some people use growth hormone as its actions elevate IGF-1. However, this study showed that older men who had higher levels of IGF-I were more likely to die from a cancer-related cause in the following 18 years than men with lower levels.
The study was accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
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