The Hormone deprivation therapy, also known as androgen depletion therapy, basically involves androgen depletion through chemical castration with drugs such as leuprolide and goserelin.
Prostate cancer patients who are prescribed these drugs often stay on them for the duration of their life, and the researchers have been documenting the potential adverse effects associated with their use.
New […]

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In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.
The drugs blocked an enzyme and opened blood vessels to tumors but not normal brain. According to the researchers, these findings may have […]

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Scientists at the Institute of Cancer Research have come up with a miraculous new drug that can potentially save the lives of thousands of prostate cancer sufferers.
According to scientists, men with aggressive and incurable prostate cancer can gain years of life with abiraterone.
Abiraterone could potentially treat up to 80percent of patients with a deadly form […]

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Scientists say a new drug which treats aggressive prostate cancer is possibly the most significant development in the field for 70 years.
The new drug Abiraterone could they say potentially treat up to 80% of patients with a deadly form of the disease which is resistant to currently available chemotherapy.
Abiraterone works by blocking the hormones which […]

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A lot of doctors give androgen deprivation therapy without any evidence that it’s a good thing for early-stage prostate cancer. One of the reasons we’re in such a quagmire on prostate cancer is so many doctors have practiced medicine not supporting the clinical trials but just treating it the way they think they ought to […]

continue reading from " Hormone therapy rates no different than ‘watchful waiting’ in prostate cancer "

Hormone therapy is the second most-used treatment after surgery for early prostate cancer that hasn’t spread, although the drugs aren’t approved for that use, researchers said. The medicines can cause side effects such as hot flashes and impotence and have been associated with osteoporosis and diabetes.
Widely used hormone-blocking drugs failed to improve survival in older […]

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Scientists at Dana-Farber Cancer Institute report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a “powerhouse” that drives runaway cell growth.
They said that drugs are on their way to clinical testing, but is hard to predict when they might become available for clinical […]

continue reading from " Researchers identify promising cancer drug target in prostate tumors "

Researchers from Oregon Health and Science University have found a new chemotherapy drug that may help treat prostate cancer.
Sagopilone, a fully synthetic derivation, is a new class of drug that inhibits growth and the spread of malignant cell, similar to docetaxel, which has been the gold standard for this type of hormone independent prostate cancer.
This […]

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A new study has shown that elderly men with higher activity of the hormone IGF-1, or insulin-growth factor, appear to have greater life expectancy and reduced cardiovascular risk.
The study showed that subjects with the lowest IGF-1 function had a significantly higher mortality rate than subjects with the highest IGF-1 bioactivity. These findings were especially important […]

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Recently two new studies have re-evaluated a 2003 study at the Department of Urology at the University of Texas Health Sciences Center at San Antonio and its conclusion related to use of finasteride for prostate cancer prevention. The old study conclusions suggested that while finasteride reduced prostate cancer risk by 25 percent, it appeared to […]

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