Erectile dysfunction is a clinical disorder that results from a continuous spectrum of clinical factors, including physical illness, reaction to stress and relationship difficulties. Testosterone clearly has a relevant role in all three causes. However, the usefulness of this hormone in the treatment of erectile dysfunction has not been completely clarified.
The main physiological action of testosterone in the male sexual response is to regulate the timing of the erectile process as a function of sexual desire, thereby coordinating penile erection with sex. The link between erectile dysfunction, hypogonadism and underlying disorders is nowadays well documented. The recognition of underlying disorders might be useful in motivating men with erectile dysfunction to improve their health-related lifestyle choices.

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