A new research on UT Southwestern Medical Center conducted on mice may help find an explaination why all obese people aren’t diabetic.
In this study the ‘world’s fattest mice” can overeat without developing insulin resistance or diabetes thanks to a glut of a key hormone.
Excess calories consuming usually spurs insulin resistance and diabetes, but this study shows how an abundance of adiponectin, a hormone that controls sensitivity to insulin, and a lack of leptin, a hormone that curbs appetite, help mice to store excess calories in fat tissue instead of in heart, liver or muscle tissue - places where excess fat can cause inflammation, diabetes and heart disease.

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