It has long been known that androgen deprivation therapy (ADT), when used in the long-term treatment of men with prostate cancer, is accompanied by not only hot flashes and effects on cognition but also by bone loss, increased risk for fracture, loss of muscular strength, mood disturbances, and fat-based weight gain, all of which affect physical functioning, independence, and quality of life. It has also long been known that exercise regimens appear to help some men to avoid or manage this latter group of side effects.
A group of Australian researchers has investigated the effects of a 12-month exercise program designed to load the musculoskeletal system and reduce cardiovascular and diabetes disease progression.
The authors express the hope that the results of this study will help to reduce fracture risk, improve physical and functional ability, improve quality of life, and perhaps improve survival rates in men with prostate cancer who need ADT.
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