High-flow priapism (HFP) may occur secondary to perineal trauma, congenital arterial malformations, and iatrogenic insults. Statistics show that in those cases that do not resolve spontaneously, the standard management offered is by selective embolization, resulting in resolution rates as high as 78%; however, erectile dysfunction (ED) is a frequent complication, occurring in up to 39% of cases.
A recent research at University of California San Francisco reports the use of androgen blockade (AB) to suppress nocturnal erections as an alternative treatment for HFP
According to research conclusion, AB is a successful option for treating HFP with acceptable side effects and return to baseline potency on treatment withdrawal.

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